Moses Aristophanes Kwame Gyasi was educated at Mfantsipim School, Cape Coast, and at the University of Ghana, Legon, where he obtained a B.Sc. (Administration) degree in June 1970. He was admitted into the membership of the Institute of Chartered Accountants (Ghana) in 1976.

Mr. Gyasi has had considerable experience in the profession, industry, commerce, academia and civil society institutions. He formally retired as a Senior Lecturer with the University of Ghana Legon in 2012 after 26 years of service. Before that, he worked as an accountant in various positions with many organisations including the Electricity Company of Ghana, Tema Shipyard and Drydock Corporation, Kowus Motors Ltd. and as an auditor with KPMG. For almost eight years he was a Principal Lecturer in accountancy subjects and acting head of Department at Kwara State Polytechnic, Ilorin, Nigeria, two of which were spent as the Deputy Director of the Institute of Management and Vocation, one of the four Institutes within the Polytechnic.

Mr. Gyasi has had the opportunity to offer management consultancy services to a number of companies. Apart from his professional assignments, Mr. Gyasi is a prolific writer, and a social critic (a reference made to him by the former President of the nation. Mr. Agyekum Kufuor, for his comments on issues of national interest and importance). He contributes articles in the print media, and for a period of almost twenty years contributed articles on weekly basis first in THE SPECTATOR and then in the DAILY GUIDE. He also takes part in discussions on the electronic media as well as delivers lectures at important forums. He is the author of six books on accounting and one on corruption entitled: “A Voice Against Corruption: Enough is Enough”.

Mr. Gyasi has served as a board member of many organisations including some state bodies like the New Times Corporation, Ghana Broadcasting Corporation, National Petroleum Tender Board, GETFund Mfantsipim School and private ones like Research International, Coconut Grove Hotels Ltd. and Institute of Chartered Accountants (Ghana). He joined the Ghana Integrity Initiative as a Board Member in October 2003 and later become the Board Chair until he retired in December 2019. He has served and continues to serve on various Audit Committees of a number of state organisations.
Currently, Mr. Gyasi serves as a member of the Board of Directors of the Energy Commission.
Mr. Kwame Gyasi is married with one daughter.